Highlights

  • Water influx helps cells migrate

    Clarifying the role of water influx and swelling as neutrophils migrate in response to chemoattractants.

    Tamas L Nagy, Evelyn Strickland, Orion D. Weiner
    Reviewed Preprint Updated
  • Follow the leader

    Study reveals a leader-follower relation between the two flagella responsible for moving the single-cell alga Chlamydomonas reinhardtii.

    Da Wei, Greta Quaranta ... Daniel SW Tam
    Research Article
  • Iron metabolism and cancer

    MEMO1 is an iron-binding protein that modulates iron homeostasis in cancer cells.

    Natalia Dolgova, Eva-Maria E Uhlemann ... Oleg Y Dmitriev
    Research Article Updated

Latest research

    1. Neuroscience

    Establishing synthetic ribbon-type active zones in a heterologous expression system

    Rohan Kapoor, Niko Schwenzer ... Tobias Moser
    1. Neuroscience

    Rate of brain aging associates with future executive function in Asian children and older adults

    Susan F. Cheng, Wan Lin Yue ... Juan Helen Zhou
    1. Neuroscience

    DBT is a metabolic switch for maintenance of proteostasis under proteasomal impairment

    Ran-Der Hwang, Yu-Ning Lu ... Jiou Wang
    1. Neuroscience

    Midbrain encodes sound detection behavior without auditory cortex

    Tai-Ying Lee, Yves Weissenberger ... Johannes C Dahmen
    1. Genetics and Genomics

    Post-meiotic mechanism of facultative parthenogenesis in gonochoristic whiptail lizard species

    David V Ho, Duncan Tormey ... Peter Baumann
    Facultative parthenogenesis in whiptail lizards produces genome-wide homozygosity in offspring.
    1. Biochemistry and Chemical Biology
    2. Stem Cells and Regenerative Medicine

    Targeted protein degradation systems to enhance Wnt signaling

    Parthasarathy Sampathkumar, Heekyung Jung ... Yang Li
    A novel targeted protein degradation system to achieve cell-type-specific enhancement of Wnt signaling.
    1. Genetics and Genomics

    Enhancing CRISPR prime editing by reducing misfolded pegRNA interactions

    Weiting Zhang, Karl Petri ... Jing-Ruey Joanna Yeh
    Strategic pegRNA designs and other approaches mitigating 5' and 3' interactions within pegRNAs can often lead to substantial improvements in prime editing efficiency.
    1. Computational and Systems Biology

    AI-driven Automated Discovery Tools Reveal Diverse Behavioral Competencies of Biological Networks

    Mayalen Etcheverry, Clément Moulin-Frier ... Michael Levin